Fungi causing plant death are one of the most important factors limiting tomato crop cultivation in the world. In order to evaluate the response of tomato genotypes to Rhizoctonia solani, Pythium aphanidermatum and Fusarium solani, a factorial experiment was conducted based on a completely randomized design with three replications in greenhouse of Shiraz Azad University. The genotypes included King stone, Super leader, Super stone, Red stone and Zare's local cultivar. The cultivars cultivated without a pathologist were considered as control treatment (5 treatments), combining cultivars with Fusarium, Phthium, Rhizoctonia separately, combination of cultivars with two cultivars, and combination of cultivars with all three factors The disease was treated in this experiment, which consisted of 40 treatments. The studied traits included intensity and percentage of contamination, length, fresh and dry weight of shoot and fresh and dry weight of root. The results showed that the super leader, exposed to the Rhizoctonia solani fungus, completely disappeared due to the high severity of the disease and the percentage of contamination. The Zare variety, which was exposed to Pythium aphanidermatum + Fusarium solani fungi, was found to be the lowest disease severity. Plant height in the Zare cultivar, contaminated by Pythium aphanidermatum, had no significant difference with healthy control treatment. The decrease in plant height in Super leader, which was contaminated with Rhizoctonia solani fungi and Rhizoctonia solani + Fusarium solani, was higher than other treatments. Inoculation of pathogenic factors caused fresh and dry weight of shoot in all cultivars. But among the cultivars contaminated with mushrooms, the local cultivar Zare and also King stone were less weight loss than other cultivars. The local cultivar Zare and Super stone, which were contaminated by the Pythium aphanidermatum and Fusarium solani fungi alone or in combination, had more root and fresh weight. In the Super leader, this mushroom caused the plant to completely disappear. Finally, the local cultivar Zare and King stone were also highly tolerant to bush disease, with different fungal factors, with favorable agronomic characteristics (such as fresh and dry weight of the shoot and root). Therefore, they can be recommended for planting.