Carob moth (CM), Ectomyelois ceratoniae Zeller (Lep.: Pyralidae) is the most destructive pest of pomegranate in Iran, causing considerable economic damage in spite of different mechanical and/or biological control methods. Its pheromone analogue, (Z,E)-7,9,11-dodecatrienyl formate, has offered the possibility of the control of CM by mating disruption. In this study the efficiency of mating disruption was evaluated for controlling the last generations of CM, causing the highest damage on pomegranate, by 500 g/h of SPLAT EC containing 2% of the pheromone analogue in Yazd (Iran) in 2015. The capture of monitoring traps and the number of rotten fruits were monitored in mating disruption and control (without any control method) plots. The means of trap catches and those of percentages of infested fruits in the plots were statistically compared. The capture of monitoring traps in mating disruption plot was 61% less than that in the control plot. The percentages of rotten fruits after 6, 21, 89 days and at harvest time were respectively 77±3, 58±4, 25±4 and 29±2 in mating disruption plot and respectively 47±4, 23±3, 75±3 and 12±1 in control plot. The percentages of rotten fruits were significantly different at each sampling time. The higher percentage of rotten fruits in mating disruption plot in comparison with that in control plot after 6 days evidenced the higher infestation by CM in mating disruption plot at the beginning of the experiment. The higher percentage of rotten fruits in mating disruption plot after 3 weeks was due to the present immature stages and the offspring of mated females causing damage during the first weeks of the experiment. The percentage of rotten fruits in the control plot was 3 times more than that in the mating disruption plot after 89 days, showing the efficiency of mating disruption to control the damage of CM at this time. The higher percentage of rotten fruits in mating disruption plot at harvest time was probably due to the counting of not dropped fruits infested prior the beginning of experiment.