Today, food security is one of the most important issues in human life, along with this; the issue of food safety has also been taken into consideration by consumers of agricultural products. The study took place in 2016, and residues of two high consumption insecticides, Chloropyrifos and Cypermethrin, was investigated in sugar beets of various areas (Uromieh, Khoy, Salmas, Bookan, Miandoab, Mahabad and Naghedeh) and its pulps from three sugar factory (Uromieh, Miandoab and Naghadeh) in West Azerbaijan province. In this study, High Performance Thin Layer Chromatography (HPLC) was used to determine Chloropyrifus and Cypermethrin residues in sugar beets. The results of the samples from seven different cities (Uromieh, Khoy, Salmas, Bookan, Miandoab, Mahabad and Naghedeh) showed that the chlorpyrifos insecticide in the city of Khoy had the highest residual amount, and then, the samples of Miandoab, Bookan and Salmas respectively had the highest residual. In the cities of Mahabad, Naghdeh and Uromieh, no insecticide residues were recorded. Investigation of residues of insecticides on the pulps from three factories (Miandoab, Uromieh and Naghdah) did not show any residues from the Chlorpyrifos insecticide. In the case of Cypermethrin, the results of HPLC showed that the highest amount of this insecticide belongs to Khoy city and then the highest amount is related to Bokan, Naghade, Miandoab and Uromieh. In all of these regions, the insecticide residue remained higher than the Maximum Residue limit (MRL = 0.05) for the Cypermethrin insecticide. In the cities of Mahabad and Salmas, the remains of the Cypermethrin insecticide were not reported. Also, the pulp residues from the three factories (Miandoab, Uromieh and Naghedeh) did not show any residue from the Cypermethrin insecticide.