Recently cultivation of cucurbit crops in greenhouse becomes more important, due to water crisis. Prior to the greenhouse cultivation of cucurbit crops, assessing the reaction of cultivars and local landraces to serious pests and diseases is necessary. Liriomyza sativae (Dip.: Agromyzidae) is an economic pest on cucurbit crops. In this study, damage of the leafminer on muskmelon and cantaloupe were evaluated in two separate experiments, in a randomized complete block design with 4 replications in the research greenhouse of Isfahan Agricultural and Natural Resources Research and Education Center (Isfahan, Iran). In the cantaloupe experiment, 4 local landraces (Saveh, Shahabadi, Semsory-e-varamin and Garmak-e-habibabad) and in the muskmelon experiment, two imported cultivars (Diamond and Ananasi) and 13 local landraces (Abas-shori, Jajo, Zard-e-ivanaki, Saderati, Soski, postzard-e-Aqaalian, Jalali, Sefidak-e-zabol, Qandad-e-zabol, Gorgab, Gongi, Dargazi and Khatoni) were cultivated as scaffolding in the greenhouse. Sampling was carried out on two middle plants in each plot and infestation percentage (infested leaves/ plant) was determined. However, due to differences in the number and extent of larval mines in the infested leaves, damage rating (based on a 10-degree scale) and cumulative numbers of mines were recorded using a stratified random sampling on six leaves of the selected plants. Results showed that significant differences among treatments for all three variables, in both experiments. In cantaloupe experiment, for infestation percentage, treatments were placed in two groups. The highest means belonged to Saveh and Shahabadi (42.40 and 36.74 %, respectively) and the lowest means belonged to Semsory-e-varamin and Garmak-e-habibabad (17.94 and 18.83 %, respectively). For cumulative number of mines, the highest means were found on Saveh and Shahabadi (6 and 5.62 tunnel/ leaf, respectively) and the lowest means were found on Semsory-e-varamin (2.12 tunnel/ leaf). For damage rating, Shahabadi and Semsory-e-varamin had the highest (2.25) and lowest (1.25) means, respectively. In the muskmelon experiment, the highest means belonged to Jalali and Postzard-e-aqaalian (59.88 and 51.11 %, respectively) and the lowest mean belonged to Saderati and Ananasi (20.48 and 20.83 %, respectively). For cumulative number of mines, the highest means were found on Jajo and Khatoni (7.62 and 7.50 tunnel/ leaf, respectively) and the lowest means were found on Zard-e-ivanaki and Soski (2.00 and 1.37 tunnel/ leaf, respectively). For damage rating, the highest means belonged to Jajo, Jalali and Khatoni (3.12, 3.00 and 3.12, respectively) and the lowest means belonged to Sefidak-e-zabol, Soski, Zard-e-ivanaki, Abash-shori and Diamond (1.25, 1.12, 1.12, 1.12 and 1.25, respectively). Overall, based on three selected criteria, in the greenhouse cultivation the damage of vegetable leafminer were lower on cantaloupe of Semsory-e-varamain and muskmelon of Zard-e-ivanaki and Postzard-e-aqaalian.