Rice blast disease, reported from more than 70 countries, is prevalent in almost all countries where rice is grown. Fungus Pyricularia grisea Blast agent is one of the most important diseases of rice in Iran. This disease usually causes significant economic damage to rice annually. To investigate the effect of mineral silicon and nanoparticles coupled with mineral oil, an experiment was conducted in eight treatments in paddy fields of Sari University of Agriculture and Natural Resources in the summer of 2017.Treatments include inorganic silicon and silicon nanoparticles with ratios of 1.5, 1 and 0.5 / 1000 with mineral oil of 3% compared with Nativo fungicide 1.5 / 1000 and control with three replications using completely randomized block were design. Analysis of variance of experimental data and comparison of experimental treatments using least significant difference in (LSD) at 5% level were carried out. The results revealed that there was not a significant difference between the analysis of variance of leaf blast, neck blast, yield and yield components in experimental treatments. There was a significant difference between Nativo and silicon (mineral and particles) coupled with mineral oil. The average of treatments showed that Nativo fungicide had a higher impact on leaf blast in paddy field and laboratory conditions compared to other treatments. Comparison of mean treatments showed that quantitative and qualitative yield of rice varieties of Tarom-Hashemi cultivar in treatment with Nativo was higher than that of silica and mineral silicon nanoparticles. Rice yield was higher in treatment of silicon nanoparticles than mineral silicon compared to control.