The purpose of this research was to study variation in the use of pesticides on wheat fields of khorassan razavi and the factors affecting them from the viewpoint of beneficiaries, experts and pesticide sellers. A descriptive method was used for this study. Target population of this study consisted of expert , beneficiaries and pesticide sellers of, wheat in, Khorassan Razavi,province .Some of this three group , were selected from 2014-2016 by the simple random sampling method, following the recommendation of Krejcie and Morgan. The data were collected by a questionnaire as the tool of this study. The instrument was assessed for face and content validities by a panel of experts. The reliability of the questionnaire was between 0.85- 0.91. According to the obtained results, approximately two third of the beneficiaries referred to the agricultural offices and private sectors for pest control. About 15 % of the beneficiaries said that they were aware of the consequences of their pesticide use. Also, 45 percent of the beneficiaries announced that they choose the new pesticides according to the experts' recommendations. About 10% of beneficiaries had enough information about the pesticide residue .from the experts 'point of view, low quality of pesticides was the reason of farmers' lack of satisfaction with pesticides. About 44% of the experts believed that the main basis for selecting pesticides by the beneficiaries was its rapid impact. According to the 76% of pesticide sellers, demand for Iranian pesticides was more than foreign pesticides. According to the 44% of pesticide sellers, the reason for the selection of pesticide was pesticides with greater spatial and faster effect. The majority of pesticide sellers stated that they are aware of pesticides that they sell. However, the majority of the gardeners stated that they did not have enough knowledge about the pesticides which they use. Based on the obtained results in this investigation, it was determined that the most important factors in consumption or not consumption of any of the poisons include the level of knowledge about the pesticides, and available or not available of .every pesticide, and other factors hade the next levels of importance.