Root and stem rot disease of cucumber caused by Fusarium oxysporum f. sp Radicis-cucumerinum is the most important cucumber disease in greenhouse crops in Iran.Given the hazards of chemical pesticide application, finding low-risk alternative compounds is important.In this research, the effect of some chemical salts, including di-potassium hydrogen phosphate (4,000), potassium sorbate, ammonium bicarbonate and potassium phosphate (all three with a dose of 5,000), salicylic acid (25 mM) and carbendazim (2g/L) were investigated in induction of resistance and reduction of greenhouse cucumber contamination of royal cultivar with root and stem rot disease.This experiment was conducted in greenhouse conditions in a randomized complete block design with three replications. No compound was used in the control treatment. Application of the treatments was carried out in the first step by dipping the roots in the desired combination and then by three times the spraying at intervals of two, four, six weeks. The test was carried out one week after each spraying step.The severity of infection was calculated for each treatment based on the signs of infection .Statistical analysis of the data was performed using sas software and comparison of the meanings with Duncan's multi-domain test.The results showed that all compounds used except di-potassium hydrogen phosphate were effective in reducing the severity of the disease compared with the control.In fungicidal treatment, no symptoms were observed after one month. Sorbate potassium and salicylic acid compounds with an average efficiency of control of the disease were 61.19% and 17/38% Showed superior treatment compared to control.The results of this study showed that these compounds can be used alone or alternatively with authorized to control stem and root rot disease.nd cucumber .