Boushehr province is known as a pole of tomato production at out of season in winter with over than 15000 hectares tomato plantations and 600000 tons of tomato fruits. Tomato cultivation is one of the most important crops of Iran and Boushehr province as a source of producible business for farmers. On the other hand, broomrape genera Orobanche and Philipanche are very harmful pests in tomato, eggplants, pepper and tobacco fields in Iran especially in Bushehr province. This project was carried out in a farm of susceptible variety of tomato infested with Orobanche cernua to find a chemical method to control of this parasite. The experiment was done in a complete randomized blocks design with 7 treatments on 3 times at 30, 40 and 50 days after cultivation in the farm. The treatments including 20 and 30 gr/hec. Sulfosulfuron WG75%, 30 and 40 gr/hec Rimsulfuron DF75%, and 25 and 50 ml/hec. Glyphosate SL 41% in comparison with the water spraying control treatment. The parameters for measurement were: tomato fruits quantity (number), tomato fruits yield (gram), number of broomrape stalks, broomrape wet and dry weight (gram) and observed damages measured by EWRC method. Data were analyzed by MSTAT-C and comparisons of means were tested by Duncan’s test. The results showed that spraying of rimsulfuron 40 gr/hect. with 29.92% yield increasing, 73.88% reducing of broomratpe wet weight and 70/72% reducing of that’s grow, Sulfosulfuron 30 gr/hec. with 21.36% yield increasing, 67.18% reducing of broomrape wet weight and 61.16% reducing of that’s grow and glyphosate 30 ml/hec. with 12.11% yield increasing, 70.46% reducing wet weight and 63.46% reducing of that’s grow, with a venial optical damages were affected appropriately on reduce density and weight of broomrape and improve the tomato yield respectively.